Intensive care units (ICUs) are typically designed for functionality, not hospitality. A team at Charité – University Medicine Berlin has taken on the challenge to create a more humane environment using visual, acoustic and procedural changes. The hypothesis is that clinical outcomes can be improved through human-centric lighting, lower noise levels, and undisturbed sleep. However, the efficacy of those changes hinges on the acceptance and actual implementation by the ICU staff. Moreover, doctors and nurses act in a complex stakeholder mesh including patients, relatives and hospital management, with assumed reciprocal effects in case of spatial variations. The overarching goal of this research project is to study the staff’s stance and behavior around these changes, variance in usage over time and/or between different hospitals, especially with regard to the effects on the primary objective (clinical outcomes).