Genome research, bioinformatics, gene techology and new microscopic imaging have revolutionized microbial research over the course of the last decade. Combining these possibilities allows us to identify the unknown metabolic properties of microorganisms and optimize these for sustainable production processes in biotechnology. Used for centuries to produce food, microorganisms are deployed in postmodern biotechnology as industrial platform organisms to manufacture enzymes, pharmaceuticals, biofuels, and functional foodstuffs.
The focus of our academic chair is on the genetic optimization of the agent production of pro- and eukaryotic production systems, the production and characterization of bioactive substances with help of microbial production systems, and the development of new antifungal agents and strategies. Our research also includes extensive work in the areas of quantitative biology and systems biotechnology to gain a comprehensive understanding of the cell and its dynamics. An interdisciplinary approach combining microbiology, mathematics, and engineering is essential for modeling cellular processes and using these models to exploit microorganisms in a predictable and controlled manner and achieve maximum performance capabilities.