The aim of G-WAC is to establish a German-West African Centre for Global Health and Pandemic Prevention based at the KNUST-College of Health Sciences in Kumasi, Ghana, that will address the existential threat of global pandemics to the health and welfare of people through trans- and inter-disciplinary research projects targeting both the main drivers of pandemics (e.g. health impact of wild habitat encroachment, extensive agriculture and climate change, spillover of pathogens from wild animals to humans) and the key pillars of resilient health systems in the WHO framework (e.g. effective governance, sustainable financing mechanisms, appropriate human resource capacity, availability of essential medicines and technology, reliable health information, and responsive health service delivery) using One Health approaches.