The Department of Medical Biotechnology, headed by Prof. Dr. Sina Bartfeld, develops 3D culture models based on human stem cells, so-called "organoids". Using organoids and organ-on-a-chip technology, we emulate tissues in physiology and pathology, mainly in the digestive tract and bone marrow. While asking basic mechanistic questions about infections, the innate immune response, and carcinogenesis, the group is always striving to improve in vitro models.