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2023
- Kurreck, J. (2023) Green Lab - Nachhaltigkeit im Labor – Erfahrungsbericht Zertifizierungprozess. Biospektrum 29, 554-555
- Geisler, A.; Dieringer, B.; Elsner, L.; Klingel, K.; Klopfleisch, R.; Vornlocher, H.-P.; Kurreck, J.; Fechner, H. (2023) Lipid nanoparticle-encapsulated, chemically modified anti-adenoviral siRNAs inhibit hepatic adenovirus infection in immunosuppressed Syrian hamsters. Mol. Ther. Nucl. Acids. 32, 923-936
- Mei, Y.; Wu, D.; Berg, J.; Tolksdorf, B.; Roehrs, V.; Kurreck, A.; Hiller, T.; Kurreck, J. (2023) Generation of a Perfusable 3D Lung Cancer Model by Digital Light Processing. Int J Mol Sci 24, 6071.
- Kurreck, J. (2023) Humane Leber-Chips für die präklinische Toxizitätsbeurteilung von Wirkstoffkandidaten. Biospektrum 28, 50.
- Pang, S.; Wu, D.; Gurlo, A.; Kurreck, J.; Hanaor, D. A. H. (2023) Additive manufacturing and performance of bioceramic scaffolds with different hollow strut geometries. Biofabrication 15, 025011.
- Pang, S.; Wu, D.; Yang, H.; Kamutzki, J.; Kurreck, J.; Gurlo, A.; Hanaor, D. A. H. (2023) Enhanced mechanical performance and bioactivity in strontium/copper co-substituted diopside scaffolds. Biomater. Adv. 145, 213230.
2022
- Neuhaus, W.; ..., Kurreck, J.; Spielmann, H. (2022) The Current Status and Work of Three Rs Centres and Platforms in Europe, Altern Lab Anim 50, 381-413.
- Kurreck, J. (2022) Silencing-Technologien zur Analyse von Genfunktionen. In: Kurreck, J.; Engels, J. W. Lottspeich, F. (eds.) Bioanalytik. Spektrum Verlag. 4. Auflage, Heideberg, Germany, 997-1012.
- Kurreck, J.; Lottspeich, F.; Engels, J. W. (2022) Bioanalytik – eine eigenständige Wissenschaft. In: Kurreck, J.; Engels, J. W. Lottspeich, F. (eds.) Bioanalytik. Spektrum Verlag. 4. Auflage, Heideberg, Germany, 1-10.
- Dieringer, B.; Elsner, L.; Hazini, A.; Kurreck, J.; Fechner, H. (2022) Generation of a microRNA-Regulated Oncolytic Coxsackievirus B3; Meth. Mol. Biol. 2521, 259-282.
- Al-Zeer, M.A.; Prehn, F.; Fiedler, S.; Lienert, U.; Krisch, M.; Berg, J.; Kurreck, J.; Hildebrandt, G.; Schütlke, E. (2022) Evaluating the Suitability of 3D Bioprinted Samples for Experimental Radiotherapy: A Pilot Study. Int. J. Mol. Sci. 23, 9951.
- Pang, S.; Wu, D.; Kamutzki, F; Kurreck, J; Gurlo, A.; Hanaor, D. A. H. (2022) High Performing Additively Manufactured Bone Scaffolds Based on Copper Substituted Diposide. Materials & Design 215, 110480
- Rabie, A. M. I.; Ali, A. S. M.; Al-Zeer, M. A.; Barhoum, A.; EL-Hallouty, S.; Shousha, W. G.; Berg, J.; Kurreck, J.; Khalil, A. S. G. (2022) Spontaneous Formation of 3D-Breast Cancer Tissue on Electrospun Chitosan/Poly (ethylene Oxide) Nanofibrous Scaffolds. ACS Omega 7, 2114-2126
- Hippenstiel, S.; Thöne-Reineke, C.; Kurreck, J. (2022) Einstein Center 3R für Organmodelle als Alternative zum Tierversuch. Biospektrum 28, 224
- Nejati, F.; Capitain, C.C.; Krause, J. L.; Kang, G.-U.; Riedel, R.; Chang, H.-D.; Kurreck, J.; Junne, S.; Weller, P.; Neubauer, P. (2022) Traditional Grain-Based vs. Commercial Milk Kefirs, How Different Are They? Appl. Sci. 12, 3838
2021
- Wu, D.; Berg, J.; Arlt, B.; Röhrs, V.; Al-Zeer, M. A.; Deubzer, H. E.; Kurreck, J. (2021) Bioprinted Cancer Model of Neuroblastoma in a Renal Microenvironment as an Efficiently Applicable Drug Testing Platform. Int. J. Mol. Sci. 23, 122
- Hippenstiel, S.; Thöne-Reinecke, C.; Kurreck, J. (2021) Animal experiments: EU is pushing to find substitutes fast. Nature 600, 37
- Tolksdorf, B.; Nie, C.; Niemeyer, D.; Röhrs, V.; Berg, J.; Lauster, D.; Adler, J. M.; Haag, R.; Trimpert, J.; Kaufer, B.; Drosten, C.; Kurreck, J. (2021) Inhibition of SARS‐CoV‐2 Replication by a Small Interfering RNA Targeting the Leader Sequence. Viruses 13, 2030
- Hazini, A.; Dieringer, B.; Klingel, K.; Pryshliak, M.; Geisler, A.; Kobelt, D.; Daberkow, O.; Kurreck, J.; van Linthout, S.; Fechner, H. (2021) Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H. Viruses 13, 1918
- Berg, J.; Weber, Z.; Fechler-Bitteti, M.; Hocke, A. C.; Hippenstiel, S.; Elomaa, L.; Weinhart, M.; Kurreck, J. (2021) Bioprinted Multi-Cell Type Lung Model for the Study of Viral Inhibitors. Viruses 13, 1590.
- Tolksdorf, B.; Zarif, S.; Eberle, J.; Hazini, A.; Dieringer, B.; Jönsson, F.; Kreppel, F.; Kurreck, J.; Fechner; H. (2021) Silencing of Mcl-1 Overcomes Resistance of Melanoma Cells Against TRAIL-armed Oncolytic Adenovirus by Enhancement of Apoptosis. J. Mol. Med. 99, 1279-1291.
- Geisler, A.; Hazini, A.; Heimann, L.; Kurreck, J.; Fechner, H. (2021) Coxsackievirus B3 – its potential as an oncolytic virus. Viruses 13, 718.
- Hazini, A.; Dieringer, B.; Pryshliak, M.; Knoch, K. P.; Heimann, L.; Tolksdorf, B.; Pappritz, K.; El-Shafeey, M.; Somimena, M.; Beling, A.; Kurreck, J.; Klingel, K.; Fechner, H. (2021) miR-375- and miR-1-Regulated Coxsackievirus B3 Has No Pancras and Heart Toxicity But Strong Antitumor Efficiency in Colon Carcinomas. Hum. Gene Ther. 32, 216-230.
- Berg, J.; Kurreck, J. (2021) Clean Bioprinting - Fabrication of 3D Organ Models Devoid of Animal Components. ALTEX 38, 269-288.
2020
- Schmidt, K.; Berg, J.; Roehrs, V.; Kurreck, J.; Al-Zeer, M. A. (2020) 3D-bioprinted HepaRG cultures as a model for testing long term aflatoxin B1 toxicity in vitro. Toxicol. Res. 7, 1578-1587.
- Nejati, F.; Junne, S.; Kurreck, J.; Neubauer, P. (2020) Quantification of major bacteria and yeast species in kefir consortia by multiplex TaqMan qPCR. Front. Microbiol. 11, 1291.
- Martinez-Ruiz, E. B.; Cooper, M.; Al-Zeer, M. A.; Kurreck, J.; Adrian, L.; Szewzyk, U. (2020) Manganese-oxidizing bacteria form multiple cylindrospermopsin transformation products with reduced human liver cell toxicity. Sci. Total Environ. 729, 138924.
- Valdor, M.; Wagner, A.; Fischer, H.; Röhrs, V.; Schröder, W.; Bahrenberg, G.; Welbers, A.; Fechner, H.; Kurreck, J.; Tzschentke, T. M.; Christoph, T. (2020) RNA Interference Mediated Silencing of Kv7.2 in Rat Dorsal Root Ganglion Neurons Abolishes the Antinociceptive Effect of a Selective Channel Opener. J. Pharmacol. Toxicol. Methods 103, 106693.
- Harms, D.; Choi, M.; Allers, K.; Wang, B.; Peitsch, H.; Rapp, C.-P.; Hanisch, L.; Kurreck, J.; Hofmann, J.; Bock, C.-T. (2020) Specific Circulating microRNAs during Hepatitis E Infection can serve as Indicator for Chronic Hepatitis E. Sci. Rep. 10, 5337.
- Yehia, H; Westarp, S.; Röhrs, V.; Kaspar, F.; Giessmann, R. T.; Klare, H. F. T.; Paulick, K.; Neubauer, P.; Kurreck, J.; Wagner, A. (2020) Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations. Molecules 25, 934.
- Pinkert, S.; Pryshliak, M.; Pappritz, K.; Knoch, K.; Hazini, A.; Dieringer, B.; Schaar, K.; Dong, F.; Hinze, L.; Lin, J.; Lassner, D.; Klopfleisch, R.; Solimena, M.; Tschöpe, C.; Kaya, Z.; Beling, A.; Kurreck, J.; van Linthout, S.; Klingel, K.; Fechner, H. (2020) Development of a New Mouse Model for Coxsackievirus-Induced Myocarditis by Attenuating Coxsackievirus B3 Virulence in the Pancreas. Cardiovasc. Res. 116, 1756-1766.
- Pryshliak, M.; Hazini, A.; Knoch, K.; Dieringer, B.; Tolksdorf, B.; Solimena, M.; Kurreck, J.; Pinkert, S.; Fechner, H. (2020) MiR-375-mediated Suppression of Engineered Coxsackievirus B3 in Pancratic Cells. FEBS Lett. 594, 763-775.
2019
- Pinkert, S.; Dieringer, B.; Klopfleisch, R.; Savvatis, K.; Van Linthout, S.; Pryshliak, M.; Tschope, C.; Klingel, K.; Kurreck, J.; Beling, A.; Fechner, H. (2019) Early Treatment of Coxsackievirus B3-Infected Animals with Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy. Circ. Heart Fail. 12, e005250.
- Al-Zeer, M.A.; Dutkiewicz, M.; von Hacht, A.; Kreuzmann, D.; Röhrs, V.; Kurreck, J. (2019) Alternatively spliced variants of the 5’-UTR of the ARPC2 mRNA regulate translation by an internal ribosome entry site (IRES) harboring a guanine quadruplex motif. RNA Biol. 16, 1622-1632.
- Vester, K.; Eravci, M.; Serikawa, T.; Schütze, T.; Weise, C.; Kurreck, J. (2019) RNAi-mediated knockdown of the Rhau helicase preferentially depletes Proteins with a Guanine-quadruplex motif in the 5'-UTR of their mRNA. Biochim. Biophy. Res. Commun. 508, 756-761.
- Weinhart, M.; Hocke, A.C.; Hippenstiel, S.; Kurreck, J.; Hedtrich, S. (2019) 3D Organ Models - Revolution in Pharmacological Research? Pharmacol. Res. 139, 446-451.
- Al-Zeer, M.; Kurreck, J. (2019) Deciphering the Enigmatic Biological Functions of RNA Guanine-Quadruplex Motifs in Human Cells. Biochemistry 59, 305-311.
2018
- Hiller, T.; Berg, J.; Elomaa, L.; Röhrs, V.; Ullah, I.; Schaar, K.; Dietrich, A. C.; Al-Zeer, M.; Kurtz, A.; Hocke, A. C.; Hippenstiel, S.; Fechner, H.; Weinhart, M.; Kurreck, J. (2018) Generation of a 3D liver model comprising human extracellular matrix in an alginate-gelatine-based bioink by extrusion bioprinting for infection and transduction studies. Int. J. Mol. Sci. 19, 3129.
- Berg, J.; Hiller, T.; Kissner, M.S.; Qazi, T.; Duda, G.N.; Hocke, A.C.; Hippenstiel, S.; Elomaa, L.; Weinhart, M.; Fahrenson, C.; Kurreck, J. (2018) Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A Virus. Sci. Rep. 8, 13877.
- Pappritz, K.; Savvatis, K.; Miteva, K.; Kerim, B.; Dong, F.; Fechner, H.; Müller, I.; Brandt, C.; Lopez, B.; González, A.; Ravassa, S.; Klingel, K.; Diez, J.;Reinke, P.; Volk, H. D.; Van Linthout, S.; Tschöpe, C. (2018) Immunomodulation by adoptive regulatory T-cell transfer improves Coxsackievirus B3-induced myocarditis. FASEB J. 32, 6066–6078.
- Hazini, A.; Pryshliak, M.; Brückner, V.; Klingel, K.; Sauter, M.; Pinkert, S.; Kurreck, J.; Fechner, H. (2018) Heparan Sulfate Binding Coxsackievirus B3 Strain PD: A Novel Avirulent Oncolytic Agent Against Human Colorectal Carcinoma. Hum. Gene Ther. 29, 1301-1314.
- Hübner, D.; Jahn, K.; Pinkert, S.; Böhnke, J.; Jung, M.; Fechner, H.; Rujscu, D.; Liebert, U. G.; Claus, C. (2018) Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis. ACS Infect Dis. 8, 886-897.
- Wade, E.; Kurreck, J. (2018) The use of oligonucleotides as tools in cell biology. In: Lottspeich, F.; Engels, J. (Eds.) Bioanalytics: Analytical Methods and Concepts in Biochemistry and Molecular Biology. Wiley-VCH, 959-976.
- Loebel, M.; Holzhauser, L.; Hartwig, J.A.; Shukla, P.C.; Savvatis, K.; Jenke, A.; Gast, M.; Escher, F.; Becker, S.C.; Bauer, S. ... Pinkert, S.; Fechner, H. et al. (2018) The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis. Eur. Heart J. 39, 876-887.
- Valdor, M.; Wagner, A.; Röhrs, V.; Berg, J.; Fechner, H.; Schröder, W.; Tzschentke, T.M.; Bahrenberg, G.; Christoph, T.; Kurreck, J. (2018) RNA interference-based functional knockdown of the voltage gated potassium channel Kv7.2 in dorsal root Ganglion Neurons after in vitro and in vivo gene Transfer by adeno-associated virus (AAV) vector. Mol. Pain 14, 1-14.
- Serikawa, T.; Spanos, C.; von Hacht, A.; Budisa, N.; Rappsilber, J; Kurreck, J. (2018) Comprehensive Identification of Proteins Binding to RNA G-quadruplex motifs in the 5' UTR of tumor-associated mRNAs. Biochimie 144, 169-184.
2017
- Tschope, C.; Muller, I.; Xia, Y.; Savvatis, K.; Pappritz, K.; Pinkert, S.; Lassner, D.; Heimesaat, M.M.; Spillmann, F.; Miteva, K.; Bereswill, S.; Schultheiss, H.P.; Fechner, H.; Pieske, B.; Kuhl, U.; Van Linthout, S. (2018) NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail 10, e00387.
- Kurreck, J. (2017) Rethinking Delivery: Viral Vectors and RNA Interference. J. RNAi Gene Silencing 13, 545-547.
- Serikawa, T.; Eberle, J.; Kurreck, J. (2017) Effects of genomic disruption of a Guanine quadruplex in the 5’ UTR of the Bcl-2 mRNA in melanoma cells. FEBS Lett. 591, 3649-3659.
- Schaar, K.; Geisler, A.; Kraus, M.; Pinkert, S.; Pryshilak, M.; Spencer, J.F.; Tollefson, A.E.; Ying, B.; Kurreck, J. Wold, W.S.; Klopfleisch, R.; Toth, K.; Fechner, H. (2017) Anti-adenoviral artificial microRNAs expressed from AAV9 vectors inhibit human adenovirus infection in immunosuppressed Syrian hamsters. Mol. Ther. Nucleic Acids 8, 300-316.
- Ungerechts, G.; Engeland, C.E.; Buchholz, C.J.; Eberle, J.; Fechner, H.; Geletneky, K.; Holm, P.S.; Kreppel, F.; Kuhnel, F.; Lang, K.S. et al. (2017) Virotherapy Research in Germany: From Engineering to Translation. Hum. Gene Ther. 28, 800-819.
- Hubner, D.; Jahn, K.; Pinkert, S.; Bohnke, J.; Jung, M.; Fechner, H.; Rujescu, D.; Liebert, U.G.; Claus, C. (2017) Infection of iPSC Lines with Miscarriage-Associated Coxsackievirus and Measles Virus and Teratogenic Rubella Virus as a Model for Viral Impairment of Early Human Embryogenesis. ACS Infect. Dis. 3, 886-897.
- Wagner, A., Kurreck, J. (2017) Antisense DNA in eukaryotes. In: Reference Module in Life Sciences, Elsevier, ISBN 9780128096338.
- Fechner, H., Vetter, R., Kurreck, J., Poller, W. (2017) Silencing genes in the heart: AAV vectors for cardiac gene silencing. Methods Mol Biol. 1521, 17-39.
2016
- Schaar, K., Röger, C., Pozzuto, T., Kurreck, J., Pinkert, S., Fechner, H. (2017) Biological antivirals for treatment of adenovirus infections. Antivir Ther. 21, 559-566
- Pinkert, S., Dieringer, B., Diedrich, S., Zeichhardt, H., Kurreck, J., Fechner, H. (2016) Soluble coxsackie- and adenovirus receptor (sCAR-Fc); a highly efficient compound against laboratory and clinical strains of coxsackie-B-Virus. Antiviral Res. 136, 1-8.
- Hiller, T., Röhrs, V., Materne, E.-M.; Wagner, A., Fechner, H., Lauster, R., Kurreck, J. (2016) Study of viral vectors in a three-dimensional liver model repopulated with the human hepatocellular carcinoma cell line HepG2. J. Vis. Exp. 116, e54633.
- Geisler, A., Fechner, H. (2016) MicroRNA-regulated viral vectors for gene therapy. World J. Exp. Med. 6, 37-54.
- Pinkert, S., Röger, C., Kurreck, J., Bergelson, J., Fechner, H. (2016) The coxsackievirus and adenovirus receptor: glycosylation and the extracellular D2 Domain are not required for coxsackievirus B3 infection. J Virol. 90, 5601-5619.
2015
- Hoan, N. X., Tong, H. V., Hecht, N., Sy, B. T., Marcinek, P., Meyer, C. G., Song, L. H., Toan, N. L., Kurreck, J., Kremsner, P. G., Bock, C. T., Velavan, T. P. (2015). Hepatitis E virus superinfection and clinical progression in hepatitis B patients. EBioMedicine 2, 2080-2086.
- Wagner, A., Röhrs, V., Materne, E.-M., Hiller, T., Kedzierski, R., Fechner, H., Lauster, R., Kurreck, J. (2015) Use of a three-dimensional humanized liver model for the study of viral gene vectors. J. Biotechnol. 212, 134–143.
- Wagner, A., Bock, C.-T., Fechner, H., Kurreck, J. (2015) Application of modified antisense Oligonucleotides and siRNAs as antiviral drugs. Future Med. Chem. 7, 1637–1642.
- Dutkiewicz, M., Ojdowska, A., Kuczynski, J., Lindig, V., Zeichhardt, H., Kurreck, J., Ciesiołka, J (2015) Targeting Highly Structured RNA by Cooperative Action of siRNAs and Helper Antisense Oligomers in Living Cells. PLoS One 10, e0136395.
- Schmidt-Lucke, C., Zobel, T., Schrepfer, S., Kuhl, U., Wang, D., Klingel, K., Becher, P.M., Fechner, H., Pozzuto, T., Van Linthout, S., Lassner, D., Spillmann, F., Escher, F., Holinski, S., Volk, H.D., Schultheiss, H.P., Tschope, C. (2015) Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy. J. Infect. Dis. 2012, 1070-1081.
- Pozzuto, T, Röger, C, Kurreck, J., Fechner, H. (2015) Enhanced suppression of adenovirus replication by triple combination of anti-adenoviral siRNAs, soluble adenovirus receptor trap sCAR-Fc and cidofovir. Antiviral Res. 120, 72-78.
- Röger, C., Pozzuto, T., Kloppfleisch, R., Kurreck, J., Pinkert, S., Fechner, H. (2015) Expression of an engineered soluble coxsackievirus and adenovirus receptor by a dimeric AAV9 vector inhibits adenovirus infection in mice. Gene Ther. 22, 458-66.
- Stein, E., Pinkert, S., Becher, M. P., Geisler, A., Zeichhardt, H., Klopfeisch, R., Poller, W., Tschöpe, C., Lassner, D., Fechner, H., Kurreck, J. (2015) Combination of RNA interference and virus receptor trap exerts additive antiviral activity in coxsackievirus B3-induced myocarditis in mice. J. Infect. Dis. 211, 613-622.
2014
- Milbradt, J., Kraut, A., Hutterer, C., Sonntag, E., Schmeiser, C., Ferro, M., Wagner, S., Lenac, T., Claus, C., Pinkert, S., Hamilton, S.T., Rawlinson, W.D., Stich, H., Coute, Y., Marschall, M. (2014) Proteomic analysis of the multimeric nuclear egress complex of human cytomegalovirus. Mol Cell Proteomics 13, 2132-2146.
- Jenke A, Holzhauser L, Löbel M, Savvatis K, Wilk S, Weithäuser A, Pinkert S, Tschöpe C, Klingel K, Poller W, Scheibenbogen C, Schultheiss HP, Skurk C. (2014) Adiponectin promotes coxsackievirus B3 myocarditis by suppression of acute anti-viral immune responses. Basic Res Cardiol. 109, 408.
- Freiberg F, Sauter M, Pinkert S, Govindarajan T, Kaldrack J, Thakkar M, Fechner H, Klingel K, Gotthardt M. (2014) Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor. J Virol. 88, 7345-7356.
- von Kietzell K, Pozzuto T, Heilbronn R, Grössl T, Fechner H, Weger S. (2014) Antibody-mediated enhancement (ADE) of parvovirus B19 uptake into endothelial cells mediated by a receptor for complement factor C1q. J Virol. 88, 8102-8015.
- Von Hacht, A., Seifert, O.,Menger, M., Schütze, T., Arora, A., Konthur,Z., Neubauer, P., Wagner, A., Weise, C., Kurreck, J. (2014) Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic Acids Res. 42, 6630-6644.
- Größl, T., Hammer, E., Bien-Moller, S., Geisler, A., Pinkert, S., Roger, C., Poller, W., Kurreck, J., Volker, U., Vetter, R., Fechner, H. (2014) A Novel Artificial MicroRNA Expressing AAV Vector for Phospholamban Silencing in Cadiomyocytes Improves Ca2+ Uptake into the Sarcoplasmic Reticulum. PLoS ONE 9, e92188
2013
- Wagner, A., Röhrs, V., Kedzierski, R., Fechner, H., Kurreck, J. (2013) A novel method for the quantification of adeno-associated virus (AAV) vectors for RNA interference applications using quantitative PCR and purified genomic AAV as a standard. Hum. Gene Ther. Meth. 24, 355-363.
- Brandt, M. R. G., Kirste, A. G., Pozzuto, T., Schubert, S., Kandolf, R., Fechner, H., Bock, C.-T., Kurreck, J. (2013) Adenovirus-vector mediated RNA interference for the Inhibition of human parvovirus B29 replication. Virus Res. 176, 155-160.
- Kurreck, J. (2013) Antisense DNA in Eukaryotes. In: Maloy, S., Hughes, K. (Eds.) Brenner's Encyclopedia of Genetics 2nd Edition. Vol 1. Academic Press, San Diego, 153-155.
- Geisler, A., Schon, C., Grossl, T., Pinkert, S., Stein, E.A., Kurreck, J., Vetter, R., Fechner, H. (2013) Application of Mutated miR-206 Target Sites Enables Skeletal Muscle-specific Silencing of Transgene Expression of Cardiotropic AAV9 Vectors. Mol. Ther. 21, 924-933.
- Wagner, A., Segler, L., Kleinsteuber, S., Sawers, G., Smidt, H., Lechner, U. (2013) Regulation of reductive dehalogenase gene transcription in Dehalococcoides mccartyi. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 368, 20120317.
2012
- Wagner, A., Cooper, M., Ferdi, S., Seifert, J., Adrian, L. (2012) Growth of Dehalococcoides mccartyi strain CBDB1 by reductive dehalogenation of brominated benzenes to benzene. Environ. Sci. Technol. 46, 8960-8968.
- Winter, K., von Kietzell, K., Heilbronn, R., Pozzuto, T., Fechner, H., Weger, S. (2012) Roles of E4orf6 and VA I RNA in adenovirus-mediated stimulation of human parvovirus B19 DNA replication and structural gene expression. J. Virol. 86, 5099-5109.
- Boltzen, U., Eisenreich, A., Antoniak, S., Weithaeuser, A., Fechner, H., Poller, W., Schultheiss, H.P., Mackman, N., Rauch, U. (2012) Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-alpha-induced apoptosis. J. Mol. Cell. Cardiol. 52, 1056-1065.
- Kurreck, J. (2012) Oligonucleotide als zellbiologische Werkzeuge. In: Lottspeich, F.; Engels, J. (eds.) Bioanalytik. Spektrum Verlag, 3. Auflage, Heidelberg, Germany, 1059-1076.
2011
- Geisler, A.; Jungmann, A.; Kurreck, J.; Poller, W.; Katus, H. A.; Vetter, R.; Fechner, H.; Müller, O. J. (2011) microRNA122 Regulated Transgene Expression Increases Specificity of Cardiac Gene Transfer Upon Intravenous Delivery of AAV9 Vectors. Gene Therapy 18, 199-209. [pdf full text]
- Fechner, H.; Kurreck, J.(2011) Viral vectors for RNA interference applications in cancer research and therapy. In: Kratz, F.; Senter, P.; Steinhagen, H. (Eds.) Drug Delivery in Oncology, Wiley-VCH-Verlag, Weinheim,1415-1442
- Rothe, D.; Wade, E.; Kurreck, J. (2011) Design of small interfering RNAs for antiviral applications. Methods Mol Biol. 721, 267-292. [pdf full text]
- Fechner, H.; Pinkert, S.; Geisler, A.; Poller, W.; Kurreck, J. (2011) Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections. Molecules 16, 8475-8503. [pdf full text]
- Pinkert, S., Klingel, K., Lindig, V., Dörner, A., Zeichhardt, H., Spiller, O.B., and H. Fechner (2011) Virus host co-evolution in a persistent CVB3 infected cardiomyocyte cell line. J. Virol. 85, 13409-13419.
- Claus, C., S. Chey, S. Heinrich, M. Reins, B. Richardt, S. Pinkert, H. Fechner, F. Gaunitz, I. Schäfer, P. Seibel, and U.G. Liebert. (2011) Involvement of p32 and microtubules in modulation of mitochondrial functions by rubella virus. J. Virol. 85, 3881-3892.
- Pozzuto, T., K. von Kietzell, T. Bock, C. Schmidt-Lucke, W. Poller, T. Zobel, D. Lassner, H. Zeichhardt, S. Weger, and H. Fechner. (2011) Transactivation of human parvovirus B19 gene expression in endothelial cells by adenoviral helper functions. Virology 411, 50-64.
- Vetter, R., U. Rehfeld, C. Reissfelder, H. Fechner, H., E. Seppet, and R. Kreutz. (2011) Decreased cardiac SERCA2 expression, SR Ca uptake and contractile function in hypothyroidism are attenuated in SERCA2 overexpressing transgenic rats. Am. J. Physiol - Heart Circ. Physiol. 300, H943-50.
- Sipo, I., M. Knauf, H. Fechner, W. Poller, O. Planz, R. Kurth, and S. Norley. (2011) Vaccine protection against lethal homologous and heterologous challenge using recombinant AAV vectors expressing codon-optimized genes from pandemic swine origin influenza virus (SOIV). Vaccine 29, 1690-1699.
- Fecker, L. F., S. Ruckert, B. M. Kurbanov, M. Schmude, E. Stockfleth, H. Fechner, and J. Eberle. (2011) Efficient melanoma cell killing and reduced melanoma growth in mice by a selective replicating adenovirus armed with TNF-related apoptosis inducing ligand. Hum. Gene Ther. 22,405-417.
- Marco-Urrea, E.; Paul, S.; Khodaverdi, V.; Seifert, J.; von Bergen, M.; Kretzschmar, U.; Adrian, L. (2011) Identification and Characterization of a Re-Citrate Synthase in Dehalococcoides strain CBDBI. J. Bacteriol. 193, 5171-5178
2010
- Eckstein, A.; Grossl, T.; Geisler, A.; Wang, X.; Pinkert, S.; Pozzuto, T.; Schwer, C.; Kurreck, J.; Weger, S.; Vetter, R.; Poller, W.; Fechner, H. (2010) Inhibition of adenovirus infections by siRNA-mediated silencing of early and late adenoviral gene functions. Antiviral Res. 88, 86-94 [pdf full text]
- Rothe, D.; Wajant, G.; Grunert, H.-P.; Zeichhardt, H.; Fechner, H.; Kurreck, J. (2010) Rapid construction of Adeno-associated virus (AAV) vectors expressing multiple short hairpin RNAs with high antiviral activity against echovirus 30. Oligonucleotides 20, 191-198. [pdf full text]
- Kurreck, J. (2010) Proof of RNA interference in humans after systematic delivery of siRNAs. Angew. Chem. Int. Ed. 49, 6258-6259. [abstract]
- Werk, D.; Wengel, J.; Wengel, S. W.; Grunert, H.P.; Zeichhardt, H.; Kurreck, J. (2009) Application of small interfering RNAs modified by unlocked nucleic acid (UNA) to inhibit the heart-pathogenic coxsackievirus B3. FEBS Lett. 584, 591-598. [pdf full text]
- Poller, W., Hajjar, R., Schultheiss, H.-P., Fechner, H. (2010). Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure. Cardiovasc Res. 86, 353-364.
- S. Mern, Demissew; Ha, Seung-Wook; Khodaverdi, V.; Gliese, N.; Görisch, H. (2010) A complex regulatory network controls aerobic ethanol oxidation in Pseudomonas aeruginosa:indication of four levels of sensor kinases and response regulators. Microbiology 156: 1505-1516.
- Kretzschmar, U.; Khodaverdi, V.; Adrian, L. (2010) Transcriptional regulation of the acetyl-CoA synthetase gene acsA in Pseudomonas aeruginosa. Arch Microbiol. 2010, 685-690.